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According to the American Association of Clinical Endocrinologists and American College of Endocrinology (AACE/ACE) Obesity Clinical Practice Guidelines, all patients undergoing weight loss therapy should be monitored for mood disorders, depression, and suicidal ideation

There are some lab markers that may be helpful in addressing MCAS: DAO enzymes this is an enzyme that breaks down histamine, so checking for deficiencies can be helpful

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