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It has been reported that GSH can couple to the tocopherol system by directly reducing the tocopherol radical 41

Crane, R

doi: 10.1016/j.celrep.2019.12.078 48

However, several weeks is the upper limit for room temperature viability

The overwhelming dominance of ROS generated by enzymes like NADPH oxidases and xanthine oxidase over antioxidants like superoxide dismutase causes cell injury and tissue damage through direct injury, lipid peroxidation and protein oxidation leading to protease release and antioxidant and antiprotease enzyme inactivation as well as alteration of transcription factors activator protein-1 and NFB

Funding This study was supported by the Medical Science Research Program of Hebei Province (20220709), the Government Funded Clinical Medicine Excellent Talent Training Project (ZF2022034), and the Hebei Natural Science Foundation (H2022316005)