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Oral supplements face challenges in the digestive system, where absorption can be low, mainly in those with certain gut issues

Neher K.-D., Vinzenz von Paul Hospital, Rottweil, Department of Neurology

Vitamin C in extremely high doses (more than 1000 mg taken with a b12 supplement) may reduce b12 absorption when taken together

It is not permitted to perform homocysteine testing to confirm vitamin B12 deficit