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A marked depletion of beneficial taxa was identified, including a significant reduction in Ligilactobacillusa probiotic genus important for mucosal immunityas well as a pronounced decrease in Butyrivibrio, a key butyrate producer essential for gut barrier integrity, and a substantial decline in [Eubacterium]_siraeum_group, which is involved in SCFA production

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It plays an important role in scavenging reac

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This ultimately enhances the viability and GSH content of HL-1 mouse cardiomyocytes while decreasing Fe 2+ , ROS, and ACSL4 expression levels [130]

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