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(Deficiencies in these vitamins can lead to various health issues, such as fatigue, weakness, anemia, nerve damage, skin disorders and cognitive problems.) Energy production- B vitamins are essential for converting carbohydrates, fats, and proteins into energy

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In hepatocellular carcinoma, tumor cells outcompete macrophages for iron by upregulating TFRC, shifting TAMs toward an M2-like phenotype that enhances immune suppression (Fig

Mechanisms of chemotherapy-induced human ovarian aging: double strand DNA breaks and microvascular compromise [J]

These findings present significant implications for understanding how blocking or engaging the PD-L1:PD-1 signaling axis may influence apoptosis sensitivity in both normal and exhausted T cells to alter adaptive immune responses