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Small-molecule TKIs include imatinib, dasatinib, nilotinib, ponatinib, bosutinib, sorafenib, sunitinib, pazopanib, axitinib, vandetanib, dovitinib, vemurafenib, dabrafenib, and ruxolitinib

It directly impacts both measured outcomes and dropout rates due to nausea

The clinical evidence base for these agents, both individually and in combination, is still emerging

Third, BPC-157 increases tendon fibroblast outgrowth and migration in vitro under stress conditions, suggesting a direct cellular effect on the repair cell population