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doi: 10.1210/jcem.80.11.7593420

When the tumor volume reached approximately 200 mm, the mice were intravenously administered with Cy7.5-labeled NP4 at a dosage of 2 mg/kg

This review describes the recent advancements in the application of NPTAs for AD treatment, focusing on the pathogenesis of AD, the processes by which NPTAs enter the brain, the mechanism of NPTAs in AD theranostics, and notably, the recent developments concerning various categories of NPTAs, including inorganic nanoparticles, two-dimensional nanomaterials, metal-organic frameworks, organic polymer nanoparticles, biomimetic modified nano-delivery systems, peptide-modified nano-delivery systems, and liposomes in the field of AD treatment (Fig

GSH cleaved the nitroazo-aryl-ether group connecting fluorescence and the fluorescence quenching unit, which turn-on the fluorescence [72]

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The desalted sample was further purified by cation exchange chromatography (column: Hitrap SP, from GE healthcare) equilibrated with buffer A