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First, under conditions of nutritional ketosis, -HB constitutes the principal KB in systemic circulation, representing the majority of the dynamic range in circulating ketone concentrations

12 , e2409344 (2025)

To this end, the Pmc4 mediator subunit was fused to a degron, and we found that IAA17 in combination with the two F-box proteins atAFB2 and osTIR1 was most effective (Supplementary Fig

Abstract Parkinsons disease (PD) is a common neurodegenerative disorder caused by a spread of misfolded -synuclein and ascending neuronal degeneration mainly in dopaminergic neurons, leading to progressive nigrostriatal dysfunction and disruption of other pathways

This deficiency creates a cycle: low glutathione leads to more oxidative stress, which leads to more skin reactivity, which further depletes glutathione

Conclusion This study suggests that innate and adaptive immune cells have distinct distribution profiles in the salivary glandular tissues of patients with pSS and highlights mitochondrial metabolic pathways that may contribute to disease progression