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p53 is upregulated during MSC senescence and osteogenesis, correlating with increased expression of miR-145a, which is induced by p53

l , MEJNES2019 (control ( n = 7)

3c, Supplementary Fig

Additionally, it indirectly reduces A2E photooxidation, lowers methylglyoxal levels, and inhibits the upregulation of the receptor for advanced end glycation products [245, 248]