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sinensis is made mostly from proteins, peptides, polyamine, both important amino acids, and other unusual cyclic dipeptides such as cyclo-[Gly-Pro-], cyclo-[Leu-Pro-], cyclo-[Val-Pro] and cyclo-[Thr-Leu]

Exposure to these compounds, particularly through inhalation or prolonged contact with their metabolic byproducts, markedly increases the risk of developing bladder cancer (Cohen, 1983