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Naltrexone is FDA-approved in higher doses for treating opioid and alcohol dependence

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a study recruited 660 patients with PSCI and found that after an 8-week course of scalp acupuncture treatment, interactive dynamic scalp acupuncture (IDSA) not only significantly improved cognitive function, but also reduced depression and anxiety, improving patients self-care ability, that is better than simple combination therapy (SCT) and traditional scalp acupuncture (TSA) (Zhang S

If a user responds well at 5 mg, they can step to 7.5 mg as a gentler increase rather than doubling to 10 mg

Pawlak R

Muscle Nerve 44 (6), 947956