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10.1016/j.taap.2019.114874 Toxicol

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Ceruloplasmin (Cp) is a Cu-containing ferroxidase that exhibits antioxidant functions in part by oxidizing toxic Fe 2+ to nontoxic Fe 3+ iron, thus maintaining iron homeostasis

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3-PH can obtain an amino group from glutamate and form 3-phosphoserine (3-PS) through phosphoserine transaminase (PSAT) followed by dephosphorylation through serine phosphatase (PSPH) to finally produce serine (Figure 1)