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Metabolic profiling of cell growth and death in cancer: applications in drug discovery

Ethical Approval All experimental procedures were conducted according to the Animal (Scientific Procedures) Act 1986 Amendment Regulations 2012 (SI 4 2012/3039), and in accordance with UK Home Office welfare guidelines and project license restrictions

The strains listed in Table 1 are exemplary microorganisms that have successfully progressed through this procedure

Moreover, regression of liver fibrosis was decreased in HSC Ets1 mice compared to Ets1 flox/flox mice

8 Overall survival improvements were also noted in the CASTOR and POLLUX studies with the addition of daratumamab