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Clinical studies on microneedling with topical treatments show 82% higher response rates compared to topical application alone (Dhurat et al

High-affinity or multivalent binding can cause receptor clustering and degradation, whereas moderate-affinity, monovalent binding promotes recycling and productive transport

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This 'genetic reprogramming' helps your skin produce more collagen and elastin, form new blood vessels for better nutrient delivery, and boost its natural defenses, all while calming inflammation

International journal of physiology, pathophysiology and pharmacology , 10 (3), 132138