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Alzheimers disease pathology propagation by exosomes containing toxic amyloid-beta oligomers

We believe that when you understand how your body works, you can make better choices for your health

Each animals colon was dissected to measure length and weight

The retina and lens of the eye have very low Sorbitol dehydrogenase activity and therefore accumulation of sorbitol may lead to diabetic retinopathy

In vivo toxicity of GNCsiRNA Free siRNA duplexes are potent to activate the mammalian innate immune system, and lead to systemic inflammation in vivo through inducing high levels of inflammatory cytokines 45,46 , thus the inflammatory responses by siRNA can result in significant toxicities in vivo