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Correlation analysis of serum IGF-1 and IL-6 and urinary albumin/creatinine ratio in patients with type 2 diabetic kidney disease

Preclinical findings derived from cellular and animal models are distinguished from translational observations and human data, including pilot studies, observational cohorts, and randomized clinical trials

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Toll-like receptors: sensing and reacting to diabetic injury in the kidney

IGFBPs can also act to guide IGF-1 to specific tissues, or even to inhibit or potentiate IGF-1 actions by acting as an independent substrate for the IGF-1R and/or other specific membrane, intracellular or nuclear receptors [9395]