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The 12 mg trial dose is rarely described in community references because the GI burden was the rate-limiting factor in the trial

But with so many skin lightening options out there, how safe and effective is this treatment

*Correspondence: Silke Keiner, [email protected] This article was submitted to Neurogenesis, a section of the journal Frontiers in Neuroscience Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

The medicine is designed to be administered less frequently than Wegovy and Zepbound with injections once a month or less, compared with current drugs weekly shots

*Correspondence: Barbara Falquetto, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

I would not recommend them if you: Are currently pregnant or breastfeeding Have a known active cancer diagnosis (especially hormone-sensitive cancers) Are on immunosuppressive therapy without coordination with your specialist Have a history of severe allergic reactions to peptide-based medications As with all treatments, personalized guidance matters