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Tier 1 supplementation begins at least 4 weeks before surgery and continues through the perioperative period

Adults over 50 are more likely to develop B12 deficiency without realizing it, especially if symptoms like fatigue, memory loss, or mood changes are attributed to aging itself

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doi: 10.3389/fimmu.2018.02134 Received 09 June 2018 Accepted 29 August 2018 Published 20 September 2018 Volume 9 - 2018 Edited by Fabio Malavasi, Universit degli Studi di Torino, Italy Reviewed by Benjamin Bonavida, University of California, Los Angeles, United States

Unlike tablets or capsules, injections bypass the digestive system, which is particularly helpful for people with absorption difficulties or certain medical conditions