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Correlation heatmaps reveal pathology-related redox fingerprint patterns Prompted by the redox metabolite changes in different disease groups, we asked whether the ratios between the metabolites differed from healthy controls

Detoxification : Glutathione plays a key role in detoxifying harmful substances in the liver, helping to transform toxins into less harmful compounds for excretion

These data suggested that oxidative stress-induced thiol/disulfide imbalance at the stage of PSSG accumulation is the first critical checkpoint to prevent the cascading events leading to cataract formation

& Panayiotidis, M

Nonequilibrium thermodynamics of thiol/disulfide redox systems: a perspective on redox systems biology

The interaction between ferroptosis and inflammatory signaling pathways