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The researchers own conclusion was that it was well absorbed. Why that number is the whole ballgame: ~38% of an oral dose reaching circulation is a genuinely good absorption fraction for an oral compound plenty of approved oral products sit at or below that

Taking vitamin B-12 with vitamin C might reduce the available amount of vitamin B-12 in your body

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With injections and shots, the vitamins are administered directly into the muscle

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chronic liver disease and hepatitis may present with elevated levels Renal impairment : Reduced clearance can contribute to accumulation, though this is rarely clinically significant Solid tumours : Certain malignancies, particularly hepatocellular carcinoma and metastatic disease, may elevate B12 levels [3] Evidence suggests that unexplained markedly elevated B12 levels without supplementation may sometimes be associated with underlying disease