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Metformin has separately shown wound healing benefits: a 2021 randomized trial (N=108) of topical metformin on diabetic foot ulcers found a 52% complete healing rate at 12 weeks versus 31% with standard care alone (P=0.02) [11]

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reported elevated whole blood GSSG levels in clinically stable medicated schizophrenia patients [18, 31], while Raffa et al

Looking ahead, the key strategies for product innovation and differentiation are likely to focus on five main directions: expanding the therapeutic indications, achieving precision treatment with multiple biological targets, optimizing the clinical application of drug combinations, developing new formulations of oral medications, and extending the duration of drug action

Importantly, the relationship was also observed in human MS brains