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doi: 10.3389/fnut.2025.1679494 Received 04 August 2025 Revised 19 October 2025 Accepted 25 December 2025 Published 22 January 2026 Volume 12 - 2025 Edited by Manuela Machado, Escola Superior de Biotecnologia - Universidade Catlica Portuguesa, Portugal Reviewed by Ivan oa, University of Rijeka, Croatia Moumita Saha, Yale University, United States Updates Copyright 2026 Chang, Lin, Renn, Liu, Yen, Liao, Tikhonova, Amstislavskaya, Singh and Chen

Increased heme oxygenase-1 (HO-1), a product of the Nrf2 target gene, inhibits adhesion molecules such as E-selectin and vascular cell adhesion molecule-1 (VCAM-1) expressed in endothelial cells via NF-B downregulation (139)

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Ammonia lowering reverses sarcopenia of cirrhosis by restoring skeletal muscle proteostasis

Valko M, Morris H, Cronin MT (2005) Metals, toxicity and oxidative stress

doi: 10.1016/j.immuni.2005.09.010 32 WattsC