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It was withdrawn during phase 3 due to heart failure problems, but is still in clinical development for alternative indications

*Correspondence: Wiwat Chancharoenthana, [email protected]

Additionally, ATP depletion was effectively mitigated, and ROS production was reduced, with the nanoparticle system demonstrating lower ROS levels compared to untreated cells

Cell Cycle 7(14):20832089 Yuneva MO, Fan TW, Allen TD (2012) The metabolic profile of tumors depends on both the responsible genetic lesion and tissue type