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fructosamine or glycated albumin may also be considered as short-term alternatives when HbA1c is unreliable Document the timing of B12 treatment initiation in the patient's records to contextualise any HbA1c results obtained during this period This approach ensures that clinical decisions regarding diabetes diagnosis or medication adjustment are based on accurate data rather than a transiently distorted HbA1c result

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Acta Pharm (2012) 62:11522

J Neuroimmunol 125 : 170178

In other oligonucleotide mimetics, both the sugar and the internucleoside linkage, i.e., the backbone, of the nucleotide units are replaced with novel groups, although the base units are maintained for hybridization with an appropriate nucleic acid target compound

Furthermore, hydrogen is only slightly soluble in water, and the dissolved amount cannot be maintained owing to its permeability