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Increasing damage caused by ROS in the cell mainly involves telomere erosion, genome instability, DNA mutations, and changes in gene profiles in senescent cells [5, 6]

[DOI] [PMC free article] [PubMed] [Google Scholar] 2.Hayflick l, Moorhead PS

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Circulation 142 , A14387 (2020)

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EGCG from supplements reaches peak plasma concentration in 1 to 2 hours but maintains detectable hepatic concentrations for 6 to 8 hours post-dose [3]