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10.3390/biomedicines9111543 Biomedicines

344,345,346 Although some studies indicate that breast cancer patients with ER expression between 1% and 10% may exhibit reduced sensitivity to endocrine therapy, the threshold of 1% ER expression is still used in most current clinical practices to determine the need for endocrine therapy

Abstract Background Androgen receptor (AR) ligand-binding domain (LBD) mutations occur in ~20% of all castration-resistant prostate cancer (CRPC) patients

Valproic acid can be removed via hemodialysis, so decontamination isnt mandatory in the context of immediate access to hemodialysis

Inactivation of nuclear factor kappaB by soy isoflavone genistein contributes to increased apoptosis induced by chemotherapeutic agents in human cancer cells

Conversely, valproate may displace certain protein-bound drugs (e.g., phenytoin, carbamazepine, warfarin, and tolbutamide) [seeDrug Interactions (7.2)for more detailed information on the pharmacokinetic interactions of valproate with other drugs ]