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Milk Thistle Supports Glutathione for Dogs Milk thistle contains silymarin, an active compound that helps synthesize glutathione and has been shown to support liver health by reducing the negative effects of oxidative stress

BM, Basement membrane

Of these genes, four had liver-specific expression quantitative trait loci (eQTLs) meaning differential expression could be due to variants acquired from the donor liver (Table 1)

Abbreviations GSH: l-glutathione ATP: adenosine triphosphoric acid -GCS: -glutamylcysteine synthetase GS: glutathione synthetase GGT: -glutamyltranspeptidase PepT: tripeptidase CD: cysteine desulfhydrase CBL: -lyase GBE: glycogen-branching enzyme l-SDs: l-serine deaminases PK: pyruvate kinase PEP: phosphoenolpyruvic acid G6P: glucose 6-phosphate F6P: fructose 6-phosphate PFK: phosphofructose kinase IPTG: isopropyl -D-1-thiogalactopyranoside DCW: dry cell weight 2-DE: two-dimensional electrophoresis TCA: trichloroacetic acid CBB: coomassie brilliant blue EMP: embden meyerhof pathway References Meister A, Anderson ME

In Vitro Cell Dev Biol Plant 48:113119 Shao HB, Chu LY, Lu ZH, Kang CM (2008) Primary antioxidant free radical scavenging and redox signalling pathways in higher plant cells