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Metabolomics analysis identified specific anticancer components in TCW, such as 3-hydroxy-1-(4-hydroxyphenyl)propan-1-one, indole-3-carboxaldehyde, and caffeic acid

PMID: 86 NakhaeiKBagheri HosseiniSSabbaghzadeNBehmadiJBoozariM

Through an integrated comparative analysis of component absorption kinetics, cerebral distribution characteristics, and exogenous metabolites, this study aims to elucidate the in vivo metabolic trajectory of GEB constituents, providing a pharmacokinetic foundation for subsequent pharmacodynamic research targeting CIRI

10.1080/15548627.2023.2165323 119 YanJ.LiZ.LiY.ZhangY

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Also it distinguishes the different types of active substances that exhibit different degrees of protection for the nervous system and summarizes the mechanism thereof