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Targher, G

Our previous studies revealed the essential role of HGF in mechano-biology of postnatal muscle growth and regeneration centered on resident myogenic stem satellite cells, which are positioned between the basal lamina and the sarcolemma of postnatal myofibers and normally found in a mitotically and metabolically quiescent or near-dormant state (protracted G 1 phase, also referred to G 0 ) in adult muscle

Although these techniques offer high sensitivity and excellent molecular specificity, their clinical translation is limited by poor tissue penetration, dependence on exogenous tracers, and predominant use in preclinical or intraoperative experimental settings rather than routine diagnostic imaging