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Fourth, in a cell-free system, Cu(II) impairs channel gating of the 20S proteasome, but does not catalyze redox reactions (Santoro et al., 2016)

For example, it has been shown that LeuRS interacts with the Target of Rapamycin (TOR) pathway, a highly conserved metabolic pathway involved in regulation of several key processes such as energy metabolism, protein synthesis, nutrient uptake or autophagy

The findings from this study support this approach

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Di Paolo NC, Shayakhmetov DM

Superoxide dismutase oxidizes one superoxide radical to oxygen and catalyzes the reduction of another superoxide radical to H 2 O 2 , which is a less reactive molecule