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LRRK2-knockdown BV2 microglia cells are morphologically different from WT microglia and are highly motile even in the absence of any stimulator [10,143]

The enrichment analysis in LY46 and HGN under stress revealed that both genotypes share major pathways like metabolic pathways, biosynthesis of secondary metabolites, glutathione metabolism, and phenylpropanoid biosynthesis that contribute drought stress tolerance (Fig

9M), suggesting that short-term carbohydrate restoration can enhance performance in KETO-fed mice

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The bacterial Ras/Rap1 site-specific endopeptidase RRSP cleaves Ras through an atypical mechanism to disrupt Ras-ERK signaling