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It is likely that many of the other pathways that were affected by ibuprofen also show gender differences, but these pathways were not investigated in this study

For example, miR-155 promotes Th17 cell responses through multiple mechanisms

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R.BowserR.BruijinL.DupuisL.LudolphA.McgrathM.et al (2013)

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The conclusion: given the low use concentrations involved, together with the negative repeated-dose toxicity, skin irritation and sensitisation, and genotoxicity findings, the Panel determined the available data support the safe use of these ingredients in cosmetic products