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Glutathione depletion inhibits dendritic cell maturation and delayed-type hypersensitivity: implications for systemic disease and immunosenescence

Current management centers around weight loss reduction as there are no pharmacological therapies approved for the treatment of NAFLD

However, in the phase III trial (NCT01281189) with RPPX (150 mg twice daily) in 943 people with ALS, this compound failed to show any efficacy on functional and survival assessment, when compared with placebo control (Table 2) [192]

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Dolma S, Lessnick SL, Hahn WC, Stockwell BR

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