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Figure 1 Gross pathological changes expected in this disease model included increased lung mass, increased cellularity of the bronchoalveolar lavage fluid (BALF), epithelial thickening, and pockets of immune cell infiltrations in the lung parenchyma

Arlin ZA, Berman E, Gee TS, Kempin SJ, Mertelsmann R, Andreeff M , Nahmias N, Clarkson BD

These effects can be compounded by natural supplements through a variety of mechanisms, herbal stimulants, high-dose ephedra or green tea extracts, and some flavonoids increase heart rate, blood pressure, or sympathetic tone

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Collectively, these botanical agents target critical pathways associated with depression, encompassing serotonergic, dopaminergic, and noradrenergic regulation, neurogenesis, mitochondrial functionality, and immunomodulatory processes