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Low glutathione levels correlates with poor survival in AIDS patients

Subsequently, ROS harm cells by damaging important components like DNA, lipids, and proteins, which worsens the condition of already compromised neurons

The exact percentage varies depending on the body area and individual biology

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However, when intracellular ROS are increased, Trx is oxidized, thus leading to the dissociation of TXNIP from Trx, which subsequently interacts with NLRP3, leading to the assembly and activation of the NLRP3 inflammasome (84, 85)