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In addition, it is believed to increase the activity of certain nerve cells in the central nervous system

& Sweetman, A

M.LeenaarsM.Ritskes-HoitingaM.LangendamM

Nature 367 (6464), 607614

The determination of regional and age variations in the rate of desquamation: A comparison of four techniques

Although many of these are present in healthy neurons, several events can lead to their overproduction which, ultimately damages cellular components leading to neuronal dysfunction and increased severity and area of affliction in a time dependent manner 2,3,4