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[16] Pathophysiology [edit] Although the pathophysiology of HG is unclear, one of the most commonly accepted theories suggests that levels of -hCG are associated with it

The test is usually ordered by a doctor if a patient is experiencing symptoms of Vitamin B12 deficiency or if they have a condition that affects the absorption of Vitamin B12, such as pernicious anemia or Crohn's disease

Recognition dynamics of trinuclear copper cluster and associated histidine residues through conserved or semi-conserved water molecules in human Ceruloplasmin: the involvement of aspartic and glutamic acid gates

J NeuroImmune Pharmacol 4(4):389398 Motani A, Forster L, Tull S, Anggard EE, Ferns GA (1996) Insulin-like growth factor-I modulates monocyte adhesion to EAhy 926 endothelial cells

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It is very likely, therefore, that HIF-1's oxygen responsiveness resides over a permissive range of antioxidant buffering capacities, with the demonstration that the antioxidant/pro-oxidant equilibrium effectively uncouples HIF-1 activity from the normal pattern observed in response to variations in p O 2 in the alveolar epithelium [13, 14, 82]