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While the presented preclinical findings constitute a significant contribution to the search for novel ASD therapies, it is crucial to exercise caution against premature clinical extrapolations that might detract from established evidence-based interventions, including behavioral and educational support [3, 135]

Figure 1 2.1 Overproduction of ROS One hallmark feature of IBD is the overproduction of ROS, which causes dysregulation of signal transduction, an inflammatory response, and DNA damage, all of which contribute to the progression and deterioration of the disease ( 2), nitric oxide (NO), hydroxyl radical (-0H), hydroperoxyl radical (O 2 H), hydrogen peroxide (H 2 O 2 ), and singlet oxygen ( 2.2 Damage to biomolecules ROS can damage various cell biomolecules, including lipids, proteins, and DNA