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The authors found that the phenotypic correction persisted in the iPSCs and their derived neurons, with GAA-corrected neurons expressing roughly threefold frataxin in comparison to control non-GAA-edited neurons derived from non-GAA-edited iPSCs [80]

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Horwitz SM, Ansell S, Ai WZ, Barnes J, Barta SK, Clemens MW, Dogan A, Goodman AM, Goyal G, Guitart J, Halwani A, Haverkos BM, Hoppe RT, Jacobsen E, Jagadeesh D, Jones A, Kim YH, Mehta-Shah N, Olsen EA, Pro B, Rajguru SA, Rozati S, Said J, Shaver A, Shustov A, Sokol L, Torka P, Torres-Cabala C , Wilcox R, William BM, Zain J, Dwyer MA, Sundar H

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Polyphenols obtained from diverse food sources exert advantageous impacts on various metabolic problems, cognitive decline, and offer protection against conditions such as tumors and aging (510)