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Nutrients 13:3126

Rosenblum, Norman Rosenblum, William Cefalu, Dana K

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Notably, 50.7% of participants receiving CagriSema reached the BMI threshold for non-obesity by the end of the trial, compared with 10.2% of the placebo group

Nutritional status The HFR, despite increasing the elimination of uremic toxins and inflammatory markers, minimizes the loss of nutrients such as amino acids and vitamins with respect to high-flux HD and OL-HDF, which are associated with a loss amino acid l of 45 g/per session.75 In small studies It has been proven that the elimination of both essential and branched amino acids is lower with HFR than with acetate-free HDF, probably due to the absence of amino acid adsorption by the cartridge and the endogenous reinfusion of plasma.67 Another small randomized study showed less vitamin C losses in 41 patients using the HFR technique,76 while several studies have shown less albumin loss associated with HFR compared to OL-HDF.44,45,63 The reduced loss of amino acids, vitamins and albumin postulates HFR as a technique of great use in malnourished patients with nutritional supplementation requirements

Managing metabolic health sometimes involves more than one treatment