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a regioselective nitration of 14 may be used to selectively install a nitro group at the C3 position of compound 14 or the like, followed by chlorination of the quinoline-N-oxide moiety in the presence of POCl 3 to give intermediate 15

Chalmers WSK, Truyen U, Greenwood NM, Baxendale W (1999): Efficacy of feline panleucopenia vaccine to prevent infection with an isolate of CPV2b obtained from a cat

When choosing a prenatal vitamin for MTHFR mutations, it's important to look for one that contains methylfolate and folinic acid but without folic acid

Deficiency may increase bruising or bleeding

In such conformation, the terminal amine group can form salt bridge interactions with two conserved glutamates, Glu295 and Glu431