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Here, the HPA axis becomes overactive in response to stressful events, resulting in increased glucocorticoid and cortisol levels (53)

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Role of Oxidative Stress and Inflammation in Diabetic Wound Healing: Therapeutic Potential of Medicinal Plants

Relevantly, many patients tend to receive only a partially efficacious treatment due to lack of awareness of the disorder.112,113 Thus, all patients with CVS are recommended to have an individualized treatment plan for improving results (Table 3).114 Treatment protocol for patients diagnosed with CVS in the emergency room CVS: Cyclic vomiting syndrome