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In contrast, the negatively charged AH of AtSNX1 could experience repulsion from the membrane, potentially reducing its membrane-binding efficiency and impairing subsequent membrane deformation

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As mixed meal tolerance tests (MMTTs) were not performed for participants of 5 years of age or younger or at 6 weeks from diagnosis, fasting C-peptide/glucose was used rather than MMTT AUC due to larger coverage of the time series

Medically Reviewed by Eric Downing, M.D