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Cell-nonautonomous function of ceramidase in photoreceptor homeostasis

Fausto N, Campbell JS, Riehle KJ

BPC-157 is a 15-amino acid fragment of a larger human Body Protection Compound (BPC) protein found in gastric juice

Research discussions surrounding the combination of these peptides often revolve around the possibility that dual-pathway stimulation may produce more nuanced signaling patterns than isolated peptide exposure alone

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On the basis of data on irritancy in humans, a tolerable concentration can be derived as follows: 45 mg/m 3 Tolerable concentration = = 2 mg/m 3 (2000 g/m 3 ) 20 where: no effects were observed in a limited study on human volunteers at 45 mg/m 3 (Silverman et al., 1946) and 20 is the uncertainty factor (10 for intraspecies variation and 2 for the poor quality of the data)