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all 4 histamine receptors H1R-H4R are found in the digestive tract and they have excitatory actions there (ref)

B cell development in the spleen takes place in discrete steps and is determined by the quality of B cell receptor-derived signals

Cytosolic signaling protein Ecsit also localizes to mitochondria where it interacts with chaperone NDUFAF1 and functions in complex I assembly