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Description

214,215 Excessive expression of ZIP12 has been observed in schizophrenia

It induces miR-222 , which targets p27Kip1, resulting in CDK2/mTOR activation and the repression of ATGs

(Lond.) 17 , 33 (2020)

Stimulates collagen, elastin, and glycosaminoglycan synthesis

While nutritional VC intake demonstrates chemopreventive effects by scavenging carcinogen-induced reactive oxygen species (ROS) and maintaining genomic stability, high-dose intravenous VC acts as a prooxidant to selectively kill tumor cells via ROS-mediated deoxyribonucleic acid (DNA) damage, adenosine triphosphate (ATP) depletion, and HIF-1 degradation