interaction of chloroacetamide electrophiles with cellular glutathion Formation protein-derived in ribonuclease A by biologically relevant oxidants Design, synthesis, and biological evaluation
Design, synthesis, and biological evaluation of nitroisoxazole containing spiro[pyrrolidin oxindole] derivatives as novel glutathione peroxidase 4 mouse double minute 2 dual inhibitors that inhibit breast adenocarcinoma cell proliferation ScienceDirect Development of a Highly Selective Ferroptosis Inducer Targeting GPX4 with 2 Ethynylthiazole 4 carboxamide as Electrophilic Warhead Journal of Medicinal Chemistry Selective covalent targeting of GPX4 using masked nitrile oxide electrophiles Nature Chemical Biology Glutathione Dynamics in Subcellular Compartments and Implications for Drug Development PMC Application of a MALDI mass spectrometry assay to identify covalent fragments targeting the methyl lysine reader protein MPP8 SLAS Discovery Transduction of Redox Signaling by Electrophile Protein Reactions Science Signaling
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