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[DOI] [PubMed] [Google Scholar] 49.Valle L., Vilar E., Tavtigian S.V., Stoffel E.M

On top of the potential predictive value, antibodies to PTM antigens may have clinical relevance to identifying sub-populations of patients such as patients more or less likely to respond to specific therapies (i.e., DMARDs, biologics)

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Overexpression of human hepsin in adult mice with AAV administration For the APAP susceptibility test, mice were made to overexpress human hepsin in the liver through transduction with 2.5 10 10 viral genome (vg) per mouse of AAV-hHPN WT /hHPN RS /EGFP via retro-orbital injection

Published Parkinson's research used 3x/week IV infusions for defined study periods