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Mol Cell Proteom 20:1000022 Neuzil J, Dyason JC, Freeman R, Dong L-F, Prochazka L, Wang X-F, Scheffler I, Ralph SJ (2007) Mitocans as anti-cancer agents targeting mitochondria: lessons from studies with vitamin E analogues, inhibitors of complex II

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Injecting or infusing NAD+ directly is different from taking a precursor like NR or NMN, and the pharmacokinetics of a large NAD+ dose are still debated

At first glance, it may seem like higher oral doses would work better, but evidence suggests that is not always true

The Microdose GLP-1 Protocol ($129 monthly) serves patients seeking lower initial doses or those unable to tolerate standard dosing strategies

We appreciate the commenter's support for the first alternative, but for the reasons discussed above, we are finalizing the second alternative