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378,379 These metabolic abnormalities contribute to mitochondrial dysfunction

10.1097/IJG.0000000000000137 J

Symptoms can include: Temporary amnesia of the injurious event Decreased concentration or brain fog Difficulty learning new material Headache or blurred vision Sensitivity to noise or light Emotional lability (involuntary laughing or crying) Anxiety or depressed mood Fatigue Sleep dysfunction Dizziness or imbalance Nausea or vomiting Physical weakness Slurred speech 5 DANGER SIGNS Seek immediate medical attention for anyone exhibiting any of the following symptoms: A change in consciousness, manifesting as difficulty staying awake or alert, not making sense when talking, or not being able to understand what is being said Progressively worsening headache An increase in nausea or vomiting Pronounced physical weakness Slurred speech If none of the five big danger signs above are present, then it is ok to treat symptoms at home, following some basic guidelines: Plan a slow return to activity

Shock , 21, 433-437

The idea that systems (including the planet) may be close to a point of change where a small amount of force could cause a major transformation, is intuitive and powerful, especially in light of the increasing frequency of extreme weather events, and the palpable advent of the age of permanent crisis (Chakravarty, 2024)

Some phase III trials with anti-endothelial compounds have been done but the results have not been encouraging indicating that this could eventually be a rather difficult problem to solve [80]